48-Hour Rome Itinerary: Discover the Best of the City in 2 Days (+ Map)

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Are you planning to spend 2 days in Rome and searching for the best tips to include in your Rome itinerary? I’m here to assist you!

This guide will help you plan an amazing weekend in Rome, Italy— covering everything from dining options to must-see landmarks. At the end, I’ll also recommend additional activities for those who have 3 days in Rome (or longer!).

With some careful planning, you can see a lot in Rome in 48 hours. The public transportation system is quite efficient, and many of the city’s iconic sites are easily accessible on foot.


2 days in Rome itinerary - map, where to stay, and more!
2 days in Rome itinerary – map, where to stay, and more!

If you have any questions about this guide for spending two days in Rome, feel free to ask in the comments!

How This Rome Itinerary Works

This itinerary is organized to help break down your first and second days, including practical advice on visiting each site. An overview of these locations is provided before more detailed information is given!

Additionally, this guide contains answers to common questions, such as the best times to visit Rome and how to navigate around the city.

Strolling around Centrocelle in winter
Strolling around Centrocelle in winter
Strolling around Centrocelle in winter

At the end of the guide, you will find a map to help you visualize your journey, as well as additional recommendations for three days in Rome (or more!). I’ve also included options for day trips and other attractions worth exploring during a longer stay.

A section highlighting accommodations is also included. I recommend several great places in Rome that are perfect for first-time visitors. Those returning might want to consider staying a little outside the city center for a more authentic Roman experience.

If you have further questions, don’t hesitate to reach out, and I’ll do my best to assist you.

Best Time to Visit Rome

Rome is a wonderful city to visit any time of the year.

The high season typically runs from Easter (March-April) to September, thanks to the pleasant weather, although summer can be quite hot. Crowds also tend to increase around major Christian holidays, including Christmas.

View from my Rome apartment in December
View from my Rome apartment in December
View from my Rome apartment in December

If you want to bypass the large crowds and high prices, consider visiting between October and April. Just keep in mind that this time of year can be a bit rainy!

A sweet spot for visiting seems to be between March and May, where you can avoid the largest crowds while still enjoying pleasant weather.

How to Get Around Rome

In Rome, the metro, bus, tram, urban railway, and taxis are the most popular ways to get around.

Despite being the smallest metro system in Europe, you can navigate through three lines operating from 5:30 AM to 11:30 PM. On Fridays and Saturdays, the metro extends its hours until 1:30 AM. Tickets can be purchased at the stations.

Since the metro isn’t expansive, you may want to consider taking a bus. With over 350 bus lines, it can get a little overwhelming. For routes and schedules, check out the local transit website.

The Metro does stop at some popular spots in Rome!
The Metro does stop at some popular spots in Rome!
The Metro does stop at some popular spots in Rome!

Trams tend to be cleaner and quicker, but they don’t operate in the city center, which makes them less favored among tourists.

The urban railway, running on three lines—Rome-Lido, Rome-Viterbo, and Rome-Giardinetti—operates from 5:30 AM to 10:30 AM, with trains leaving every 10-20 minutes.

Of course, you can always opt for a traditional taxi, but be aware that taxi drivers in Rome have a mixed reputation, meaning you might pay more compared to other European cities.

The minimum fare on weekdays starts at 3 euros. However, using Uber in Rome is also a good option!

2 Days in Rome Itinerary: Overview

Day 1 Overview (Main Attractions)

  • Spanish Steps
  • Trevi Fountain
  • Piazza Navona
  • Pantheon
  • Altar of the Fatherland
  • Colosseum
  • Roman Forum and Palatine Hill
  • Circus Maximus
  • Dinner and drinks in Trastevere

Day 2 Overview (Vatican)

  • St. Peter’s Basilica
  • Vatican Museums
  • Sistine Chapel
  • Piazza del Popolo
  • Terrazza del Pincio

Day 1 in Rome (Main Attractions)

Spanish Steps

Begin your Roman adventure at the Spanish Steps, where Audrey Hepburn famously enjoyed her gelato in “Roman Holiday.” This iconic 138-step stone staircase connects Piazza di Spagna with Piazza Trinità dei Monti.

Constructed in the early 18th century, the steps lead you past notable landmarks like the Fontana della Barcaccia, the Keats-Shelley House, and Via dei Condotti.

Spanish Steps in Rome - an itinerary must!
Spanish Steps in Rome - an itinerary must!
Spanish Steps in Rome – an itinerary must!

The Spanish Steps are now a popular gathering spot for artists, poets, and painters. Each July, the steps are transformed into a runway for the Donne Sotto le Stelle fashion show.

If you’re visiting in spring, check the dates when the steps are adorned with thousands of blooming azaleas marking the season’s arrival.

Address: Piazza di Spagna, 00187 Roma RM, Italy

Trevi Fountain

It’s hard to imagine Rome without the stunning Trevi Fountain, located in the Piazza di Trevi, often referred to as “the jewel of water and stone.” This remarkable fountain, dating back to the Renaissance, is spectacularly built against the Palazzo Poli.

At the center, you’ll find the statue of Neptune, surrounded by majestic winged horses and tritons.

Trevi Fountain at night (it was too crowded!)
Trevi Fountain at night (it was too crowded!)
Trevi Fountain at night (it was too crowded!)

This site tends to be crowded with tourists throughout the day, making it difficult to admire the intricate details of the sculptures up close.

💥 PRO TIP: The fountain gets extremely crowded from 10 AM onwards, and the surrounding bars and restaurants keep it bustling in the evenings, too. The best time to visit is before 9 AM (the earlier, the better).

When you arrive at the Trevi Fountain, make sure to toss three coins into the water: one for returning to Rome, one for falling in love with an Italian, and the last one for marrying that special someone.

Address: Piazza di Trevi, 00187 Roma RM

Piazza Navona

The Trevi Fountain is just one of many impressive fountains you can find in Rome.

Next, head to Piazza Navona, where you’ll discover three more beautiful fountains: the Fontana dei Quattro Fiumi, the Fontana del Moro, and the Fontana del Nettuno.

An interesting tidbit is that, until the mid-19th century, the fountain drains were blocked, turning the square into a lake.

Now, it’s a charming baroque-style square, surrounded by cozy restaurants with terraces perfect for enjoying a glass of wine while soaking in the Roman atmosphere.

For a fantastic view of the square, visit Terrazzo Borromini, where you can enjoy a drink. You must also try “Il Tartuffo” at Tre Scalini, a world-famous dessert!

Address: Piazza Navona, 00186 Roma RM

Pantheon

After visiting Piazza Navona, make your way to Piazza Della Rotondo, where you’ll find the Pantheon, one of the best-preserved structures from ancient Rome.

Built in 27 BCE, this iconic building remains fully intact. The stunning details and carvings are worth your attention!

Rome's Pantheon
Rome's Pantheon
Rome’s Pantheon

One of the most impressive features is the oculus, an 8.7-meter (28 feet) diameter hole in the dome, allowing natural light to illuminate the interior, making it even more magnificent.

Visiting the Pantheon is free, but you’ll need to make an online reservation in advance on weekends and public holidays. Once you finish exploring, head to Sant’Eustachio for the best espresso paired with a cornetto.

Address: Piazza della Rotonda, 00186 Roma RM

Altar of the Fatherland

Your next stop is the Altar of the Fatherland, a magnificent 19th-century monument symbolizing a unified Italy, situated in the heart of the city.

Officially named Monumento a Vittorio Emanuele II, this grand structure provides a stunning view of both the Colosseum and the city.

Locals have nicknamed this monument “Wedding Cake” or “Typewriter” due to its unique appearance, often seeing it as an eyesore against the historical backdrop.

Whether you agree or not, it’s a worthwhile stop to include in your itinerary!

Address: Piazza Venezia, 00186 Roma RM

Colosseum

You’ve finally reached the Colosseum, a symbol of ancient Rome’s rich history and architecture. It is one of the New Seven Wonders of the World, located at Piazza del Colosseo.

Surrounded by other iconic sites like the Arch of Constantine and the Roman Forum, your combined ticket to the Colosseum also grants you access to these historical locations.

Aram at the Colosseum
Aram at the Colosseum
Aram at the Colosseum

Here, you’ll witness the Arena Floor, where gladiators fought fierce battles, and the Underground, where they and wild animals were kept in confinement. The Emperor’s Seats are also accessible, providing an impressive view of the arena.

Prepare for long lines at the ticket counter, or purchase your tickets online to save precious time (the ticket also includes a guided tour, which is fantastic).

Be sure to select a time slot when booking your tickets to ensure your itinerary stays on track!

Leave any large bags at your hotel, as you won’t be permitted entry with them. The Colosseum is wheelchair-accessible.

Address: Piazza del Colosseo, 1, 00184 Roma RM

Roman Forum and Palatine Hill

After your visit to the Colosseum, continue on to the Roman Forum and Palatine Hill, both historic sites located adjacent to the Colosseum.

The Roman Forum served as the epicenter of political, judicial, and economic activities during the Roman Empire. It was also the site where Caesar’s body was displayed following his assassination.

Exploring the Roman Forum allows you to step back in time and immerse yourself in history.

The Forum is included on your Colosseum ticket
The Forum is included on your Colosseum ticket
The Forum is included on your Colosseum ticket

Palatine Hill rises above the Forum and is where the emperor’s palaces once stood, complete with pools, fountains, and a sports stadium. Climb to the top of Palatine Hill for stunning views of Circus Maximus and the Colosseum below.

Take your time to explore the various historical structures, including the House of the Vestals, the Arch of Septimius Severus, the Temple of Saturn, and many others.

You can access both the Roman Forum and Palatine Hill with a combined ticket if you plan to visit them the same day.

Address: Via della Salara Vecchia, 5/6, 00186 Roma RM

Circus Maximus

Your final stop for the day is Circus Maximus, the largest stadium in ancient Rome, nestled between the Palatine and Aventine Hills. It once held over 150,000 spectators.

Chariot races were the main event at Circus Maximus, which involved thrilling laps around a sandy arena.

Today, the ruins of this grand stadium exist as a park where locals and visitors alike can relax after a day of sightseeing.

Entering the park is free every day from 9 AM to 7 PM.

Address: Via del Circo Massimo, 00186 Roma RM

Grab Dinner and Drinks in Trastevere

As the day winds down, treat yourself to delicious Italian cuisine in Trastevere, a lively neighborhood filled with street cafes, restaurants, and bars.

If you want a fantastic experience in Trastevere, be sure to stop by Bar San Calisto, the oldest bar in the area, which opens at 6 AM for coffee and pastries, transforms into a lively restaurant in the evening, and serves drinks until 2 AM.

Trastevere is a great place for food and drinks
Trastevere is a great place for food and drinks
Trastevere is a great place for food and drinks

For wine enthusiasts, Enoteca La Vite offers local wines by the glass alongside generous portions of snacks and marinated vegetables on the terrace.

Next to San Calisto, there’s also a modern bar featuring a unique craft cocktail menu that changes frequently.

Tasting cocktails becomes an enjoyable experience, as you can also watch skilled bartenders demonstrate their craft in mixing, straining, and juicing ingredients.

Day 2 in Rome (Vatican City)

St. Peter’s Basilica

Your second day focuses on Vatican City, starting with St. Peter’s Basilica—the world’s largest church and the Pope’s residence, a central pilgrimage site for Catholics.

Inside this Renaissance-style basilica, you’ll find incredible artworks, including Michelangelo’s Pietà, St. Peter on his throne, and the spectacular St. Peter’s Baldachin. Make sure to take the time to appreciate every detail.

St. Peter’s Basilica
St. Peter’s Basilica
St. Peter’s Basilica

Be sure to gaze up at the impressive Buonarroti Dome designed by Michelangelo, soaring to 130 meters (427 feet) high!

Remember to adhere to a dress code when visiting St. Peter’s Basilica; ensure your shoulders and knees are covered. If you have tattoos, be sure to cover them as well. You can’t bring backpacks, strollers, or large bags into the church.

Address: Piazza San Pietro, 00120 Città del Vaticano, Vatican City

Vatican Museums

After enjoying St. Peter’s Basilica, head to the Vatican Museums, which house priceless religious artifacts and a vast collection of Roman art. This expansive complex consists of 26 museums, each with its own story.

You can learn about the collections via audio guides that will guide you through key highlights such as the Gallery of the Candelabra, the Gallery of Tapestries, and the Gallery of Maps.

Plan for a visit lasting over three hours if you wish to appreciate each artwork fully.

As with most popular sites in Rome, expect large crowds, so purchasing your tickets in advance is advisable (though they may be slightly more expensive, you’ll save considerable time).

Also, keep in mind the dress code for churches and other locations in Vatican City.

Sistine Chapel

As part of your Vatican tour, don’t forget to visit the Sistine Chapel, a historic site and architectural masterpiece in its own right.

The chapel’s ceiling is iconic, adorned with frescoes created by renowned artists including Botticelli, Luca, Perugino, and Michelangelo.

Fresco at the Vatican
Fresco at the Vatican
Fresco at the Vatican

Consider visiting on Friday nights during the summer for a less crowded experience, or schedule an early bird tour before 8 AM to avoid the usual crowd surge.

Piazza del Popolo

Before concluding your day, make sure to visit Piazza del Popolo, the northern gateway to Rome and a historic entrance during the Roman Empire.

Here, you’ll find beautiful churches like Santa Maria dei Miracoli and Santa Maria in Montesanto, an Egyptian obelisk, and Santa Maria del Popolo housing masterpieces by Caravaggio.

Once in the square, take a stroll between the churches to explore popular shopping streets nearby.

Piazza del Popolo
Piazza del Popolo
Piazza del Popolo

A perfect shopping day culminates with a delightful dinner in a nearby restaurant.

If time and energy permit, consider heading to Villa Borghese, one of Europe’s largest urban parks, brimming with various activities.

However, keep in mind that exploring Villa Borghese takes more time than just an extra hour, which is why it is listed under places to visit if you happen to have more than 48 hours in Rome.

Address: Piazza del Popolo, 00187 Roma RM

Watch the Sunset at Terrazza del Pincio

As your day draws to a close, take a leisurely stroll to the Pincio terrace. This scenic overlook offers breathtaking views of Piazza del Popolo and the city beyond as the sun sets.

Sunset from Terrazza del Pincio
Sunset from Terrazza del Pincio
Sunset from Terrazza del Pincio

This attraction is free and provides beautiful memories and emotions. If you love viewpoints, you won’t find a better spot than this terrace!

Address: Salita del Pincio, 00187 Roma RM

Where to Eat (and Drink!) in Rome

Tonnarello

Located in Trastevere, Tonnarello is a well-loved restaurant that serves exquisite Italian dishes. Expect to see lines during peak meal times, but it’s always worth the wait.

Every Italian dinner should start with a bottle of red wine, so enjoy a glass while you wait for your food. For appetizers, guests rave about the bruschettas and calamari.

You’ll find an extensive menu of main courses, and whatever you choose, you can be assured it will be exceptional. Finish your meal with a cup of coffee, which comes with a complimentary plate of homemade cookies!

Pizza della Madonna dei Monti

Known for its delicious ravioli, lasagna, and pizzas, Pizzeria della Madonna dei Monti is a must-visit spot.

The restaurant is conveniently located near the Colosseum and other sightseeing areas.

Supporting local farms, this restaurant focuses on creating an ethical menu, which contributes to the fresh and flavorful dishes.

Pair your meal with delightful cordials, margaritas, or regional wines. Be sure to try their homemade beers, which are perfect for accompanying their pizzas!

Mr. 100 Tiramisu

For a quintessential Italian treat, head to Mr. 100 Tiramisu for an unforgettable dessert experience! Known for its exceptional service and delightful atmosphere, this place serves the best tiramisu in town!

Tiramisu is a must in Italy
Tiramisu is a must in Italy
Tiramisu is a must in Italy

Along with tiramisu, they also offer exquisite bruschetta, burrata salad, meat and cheese platters paired perfectly with wine, and a variety of other mouthwatering dishes you cannot miss.

The irresistible combination of delightful dessert and exceptional service makes every guest feel truly special.

Taverna Romana

Enhance your visit to Via della Madonna dei Monti with a memorable dinner at Taverna Romana, a favorite among both tourists and locals for its delicious Roman cuisine.

The menu features all the classic Italian dishes, sourced seasonally from the Lazio region of Roman countryside.

Signature dishes include gnocchi and truffle pasta. For dessert, don’t pass up the opportunity to try tiramisu or chocolate pie with espresso.

Osteria Barberini

After a leisurely walk around Piazza Barberini, make your way to Osteria Barberini, renowned for having some of the finest food in Rome (especially their truffle selections!).

In addition to truffles, this restaurant is celebrated for its authentic Italian cuisine, including delectable spaghetti carbonara, white risotto, and lasagna. Most dishes incorporate the rich flavor of truffle.

Ensure to explore the wine list that perfectly matches the delectable dishes, but don’t forget to check out the dessert menu, which features perfectly prepared strawberry tiramisu, parfait, and raspberry cheesecake!

Do you have 3 days in Rome? Or longer?

If you’re looking to extend your long weekend in Rome, here are some additional places and day trip options to consider adding to your itinerary.

Villa Borghese Grounds and Gallery

Villa Borghese, an expansive 200-acre park, is one of the largest and most beautiful spots in Rome.

Originally built for Cardinal Scipione Borghese in the 17th century, this villa houses world-class museums, including the Galleria Borghese and Casa del Cinema.

The park provides the perfect escape from bustling crowds, allowing you to enjoy nature without feeling overwhelmed.

Villa Borghese
Villa Borghese
Villa Borghese

To explore the grounds, consider renting a bike and starting at Parco dei Daini, leading you to the Borghese Gallery and the zoo.

Within Villa Borghese, there’s a charming pond where you can rent a boat for just 3 euros to enjoy a leisurely paddle.

You can view the Borghese Gallery at your own pace or opt for a guided tour. Maps are readily available throughout the park to ensure you find your way easily.

Finish your day at a small cafe in the reception area of the Borghese Gallery, enjoying snacks and pastries with coffee.

Address: Piazzale Napoleone I, 00197 Roma RM

Castel Sant’Angelo

The historic Castel Sant’Angelo is a remarkable fortress that has stood for 2,000 years, witnessing the evolution of Rome. Situated along the right bank of the Tiber River, not far from the Vatican.

A winding ramp leads through each of the fortress’s five floors. On the first level, you can see the tomb of Emperor Hadrian.

The second floor houses prison cells, while the upper levels display a collection of Renaissance paintings and sculptures. On the fourth floor, discover the beautifully decorated rooms that were once a papal residence.

Castel Sant’Angelo
Castel Sant’Angelo
Castel Sant’Angelo

Don’t miss the terrace view that overlooks the river and the bronze statue of Archangel Michael.

During peak season, expect long lines at Castel Sant’Angelo, so booking in advance is advisable.

Address: Lungotevere Castello, 50, 00193 Roma RM

Santa Maria Maggiore Basilica (Vatican)

The Basilica di Santa Maria Maggiore is one of the four major basilicas in Rome and is the largest church dedicated to the Virgin Mary.

Located atop Esquiline Hill, this 4th-century basilica features a stunning façade and exquisite interior with beautiful marble floors, columns from ancient Roman structures, and 5th-century mosaics.

Make sure to look up at the magnificent ceiling adorned with Renaissance and Baroque decorations.

Santa Maria Maggiore Basilica
Santa Maria Maggiore Basilica
Santa Maria Maggiore Basilica

The church features gold that was the first to be brought to Europe in the 1400s. It is open daily from 7 AM to 6:45 PM, and entrance is free.

Remember to dress appropriately—cover your shoulders and knees. If you can, visit after sunset to see the church beautifully illuminated by 130 light projectors.

Address: P.za di Santa Maria Maggiore, 00100 Roma RM

Walk around the Monti Neighborhood

Situated between the Colosseum and Piazza Venezia, the Monti neighborhood is known for its charming cobbled streets and trendy restaurants.

For a local experience, visit during aperitivo hours (from 6:30 PM to 8:30 PM), when people gather on the steps of the fountains to socialize.

Alternatively, start your day by visiting various attractions and enjoy breaks at cafes for snacks, coffee, and gelato.

Overlooking Monti in Rome
Overlooking Monti in Rome
Overlooking Monti in Rome

Spend the remainder of the day strolling around the neighborhood before sunset, and consider enjoying a glass of wine at one of the terrace cafes on Piazza della Madonna ai Monti. You might also opt for a food tour of Monti!

For weekend shopping, Mercato Monti offers an array of vintage and handmade items. If you arrive around lunchtime, check out L’Asino d’Oro for a meal or try traditional dishes at La Carbonara.

The National Roman Museum

The National Roman Museum is renowned for housing exceptional ancient Greco-Roman art.

This museum consists of four buildings: Palazzo Altemps, the Baths of Diocletian, Crypta Balbi, and Palazzo Massimo. Each building showcases breathtaking exhibits worth your attention.

While exploring, you’ll encounter well-preserved Roman frescoes, intricate mosaics from the 2nd century AD, and unique jewelry.

Exhibitions are organized chronologically by themes, allowing you to journey through time. The buildings are equipped with elevators and wheelchairs available for visitors with mobility issues.

Address: Largo di Villa Peretti, 2, 00185 Roma RM

Take a Day Trip to Tivoli (Villa d’Este and Villa Adriana)

A relaxing day trip to the charming town of Tivoli is a wonderful escape from the hustle and bustle of Rome.

From Rome Termini train station, a short 40-minute ride takes you to Villa d’Este, a stunning 16th-century palace noted for its picturesque gardens and magnificent fountains.

Tivoli
Tivoli
Tivoli

The Fountain of the Organ performs a stunning display every two hours, starting at 10 AM. You can also opt for an audio guide for a deeper insight into the history of the site.

Admission is free on the first Sunday of each month, so you may just be fortunate enough to enjoy this beauty at no cost. You can explore Villa d’Este from morning until sunset!

Two Days in Rome: On a Map!